What is the most common site for skeletal tuberculosis?

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Where skeletal tuberculosis most often localizes in the spine is being tested. It most commonly affects the thoracolumbar spine. This preference reflects hematogenous spread seeding the vertebral endplates, with the thoracic end and lumbar junction receiving a rich mix of arterial feeders that make this zone particularly vulnerable. Infection typically starts at the anterior part of a vertebral body and can spread to adjacent vertebrae and discs, sometimes causing collapse and a gibbus deformity. The sacrum is less commonly involved, and involvement purely in the thoracic spine, while possible, is less common than at the thoracolumbar junction.