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Multiple Choice

What is the most common causative organism for septic arthritis?

Staphylococcus aureus is the most common cause of septic arthritis. It comes from skin and mucosal surfaces and readily seeds joints during bacteremia or after injury, making acute joint infection more likely. Its ability to adhere to synovial tissue and resist immune defenses drives rapid inflammation and joint damage if not treated promptly. That strong, general tendency to cause septic arthritis across many patient groups is why this organism is the usual culprit. Other organisms show up in specific contexts: Neisseria gonorrhoeae tends to cause septic arthritis in sexually active young adults and often presents with disseminated gonococcal infection features; Streptococcus pneumoniae and Escherichia coli do appear but are less common overall and are more associated with particular risk factors like age or concurrent infections.

Staphylococcus aureus is the most common cause of septic arthritis. It comes from skin and mucosal surfaces and readily seeds joints during bacteremia or after injury, making acute joint infection more likely. Its ability to adhere to synovial tissue and resist immune defenses drives rapid inflammation and joint damage if not treated promptly. That strong, general tendency to cause septic arthritis across many patient groups is why this organism is the usual culprit. Other organisms show up in specific contexts: Neisseria gonorrhoeae tends to cause septic arthritis in sexually active young adults and often presents with disseminated gonococcal infection features; Streptococcus pneumoniae and Escherichia coli do appear but are less common overall and are more associated with particular risk factors like age or concurrent infections.