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Multiple Choice

Hemophilia is only seen in females.

Hemophilia is a genetic disorder caused by deficiencies in clotting factors, most often factor VIII or IX. It is inherited in an X-linked recessive pattern. Because males have only one X chromosome, a single mutated gene on that X leads to the condition, so hemophilia is most commonly seen in males. Females have two X chromosomes, so a single mutated copy usually makes them carriers without serious symptoms; only in rare cases—such as having two mutated X chromosomes or skewed X-inactivation—might a female show symptoms. It is not caused by a virus or bacteria. So the statement that hemophilia is only seen in females is not correct.

Hemophilia is a genetic disorder caused by deficiencies in clotting factors, most often factor VIII or IX. It is inherited in an X-linked recessive pattern. Because males have only one X chromosome, a single mutated gene on that X leads to the condition, so hemophilia is most commonly seen in males. Females have two X chromosomes, so a single mutated copy usually makes them carriers without serious symptoms; only in rare cases—such as having two mutated X chromosomes or skewed X-inactivation—might a female show symptoms. It is not caused by a virus or bacteria. So the statement that hemophilia is only seen in females is not correct.